As the number of nephrologists grew in a country of the size, population and complexity of India, a need was felt to have zonal chapters of the parent society where members could organize activities and meetings on the basis of geographic proximity. Four zonal chapters are active currently, with different level of enthusiasm and organization. All the Chapters organize an Annual Meeting.
| South Zone | Andhra Pradesh, Karnataka, Kerala, Lakshadweep, Pondichery, Tamilnadu, Andaman Nicobar | |
| President | M Jayakumar | |
| Secretary | K Sampathkumar | |
| Website | http://www.isnsc.org/ | |
| Annual meeting date | Second week of February | |
| Venue | ||
| West Zone | Daman, Diu, Goa, Gujarat, Madhya Pradesh, Maharashtra | |
| President | Umesh Khanna | |
| Secretary | ||
| Annual meeting date | Last week of September | |
| Venue | ||
| East Zone | Arunachal Pradesh, Assam, Bihar, Manipur, Meghalaya, Mizoram, Nagaland, Orissa, Sikkim, Tripua and West Bengal | |
| President | ||
| Secretary | Binod Prasad Sinha | |
| Annual meeting date | ||
| Venue | ||
| North Zone | Chandigarh, Delhi Haryana, Himachal Pradesh, Jammu & Kashmir, Punjab, Rajasthan, Uttar Pradesh | |
| President | KL Gupta | |
| Secretary | PP Varma | |
| Annual meeting date | February | |
| Venue |